Protein Name:
Protein LMBR1L
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UniprotKB/SwissProt ID: Q9D1E5 (Q9D1E5)
Gene Name:
Lmbr1l
Organism: Mus musculus (Mouse)
Function: Plays an essential role in lymphocyte development by negatively regulating the canonical Wnt signaling pathway (PubMed:31073040). In association with UBAC2 and E3 ubiquitin-protein ligase AMFR, promotes the ubiquitin-mediated degradation of CTNNB1 and Wnt receptors FZD6 and LRP6 (PubMed:31073040). LMBR1L stabilizes the beta-catenin destruction complex that is required for regulating CTNNB1 levels (PubMed:31073040). Acts as a LCN1 receptor and can mediate its endocytosis (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane. Endoplasmic reticulum membrane
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Graphical Visualization of S-nitrosylation Sites:
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