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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Heterogeneous nuclear ribonucleoprotein M

UniprotKB/SwissProt ID: Q9D0E1 (Q9D0E1)

Gene Name: Hnrnpm

Organism: Mus musculus (Mouse)

Function: Pre-mRNA binding protein in vivo, binds avidly to poly(G) and poly(U) RNA homopolymers in vitro. Involved in splicing. Acts as a receptor for carcinoembryonic antigen in Kupffer cells, may initiate a series of signaling events leading to tyrosine phosphorylation of proteins and induction of IL-1 alpha, IL-6, IL-10 and tumor necrosis factor alpha cytokines (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR024666 HnRNP_M_PY-NLS
IPR034990 hnRNPM_RRM3
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR035979 RBD_domain_sf
IPR000504 RRM_dom
IPR050374 RRT5_SRSF_SR

The S-nitrosylation sites of Q9D0E1

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 113 LMDAEGKSRG C AVVEFKMEES  CCCHHHHHHH H HHCCCCCCHH  2.23% 20925432
2 652 GHAPGVARKA C QIFVRNLPFD  CCCHHHHHHH H HHCCCCCCHH  3.41%
3 675 WKMLKDKFNE C GHVLYADIKM  CCCHHHHHHH H HHCCCCCCHH  4.85%
4 693 IKMENGKSKG C GVVKFESPEV  CCCHHHHHHH H HHCCCCCCHH  4.26%