\
logo
  Home | Contact us | Browse | Quick Search by UniProtKB ID, Keyword, PDBID

Menu:

Latest news:

Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

Read more...


Protein Name: Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

UniprotKB/SwissProt ID: Q9D051 (Q9D051)

Gene Name: Pdhb

Organism: Mus musculus (Mouse)

Function: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion matrix

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR027110 PDHB_mito-type
IPR029061 THDP-binding
IPR009014 Transketo_C/PFOR_II
IPR005475 Transketolase-like_Pyr-bd
IPR033248 Transketolase_C

The S-nitrosylation sites of Q9D051

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 161 SAGVAAQHSQ C FAAWYGHCPG  CCHHHHHHCC H HHHHHHHHHH  2.55%
2 169 SQCFAAWYGH C PGLKVVSPWN  CCHHHHHHCC H HHHHHHHHHH  2.19%
3 249 VVAHSRPVGH C LEAAAVLSKE  CCHHHHHHCC H HHHHHHHHHH  2.78%
4 263 AAVLSKEGIE C EVINLRTIRP  CCHHHHHHCC H HHHHHHHHHH  4.84% 21278135
5 306 WPQFGVGAEI C ARIMEGPAFN  CCHHHHHHCC H HHHHHHHHHH  1.24% 21278135