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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Mitochondrial import receptor subunit TOM70

UniprotKB/SwissProt ID: Q9CZW5 (Q9CZW5)

Gene Name: Tomm70

Organism: Mus musculus (Mouse)

Function: Acts as a receptor of the preprotein translocase complex of the outer mitochondrial membrane (TOM complex). Recognizes and mediates the translocation of mitochondrial preproteins from the cytosol into the mitochondria in a chaperone dependent manner (By similarity). Mediates TBK1 and IRF3 activation induced by MAVS in response to virus infection and promotes host antiviral responses during virus infection (PubMed:20628368)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion outer membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR011990 TPR-like_helical_dom_sf
IPR019734 TPR_rpt

The S-nitrosylation sites of Q9CZW5

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 179 LQKWKEVAQD C TKAVELNPKY  CCCCHHHHHH H HHHHCCCCCC  2.53% 21278135
2 505 FGKADEMYDK C IDLEPDNATT  CCCCHHHHHH H HHHHCCCCCC  2.4%