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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Succinate dehydrogenase cytochrome b560 subunit, mitochondrial

UniprotKB/SwissProt ID: Q9CZB0 (Q9CZB0)

Gene Name: Sdhc

Organism: Mus musculus (Mouse)

Function: Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) (By similarity). SDH also oxidizes malate to the non-canonical enol form of oxaloacetate, enol-oxaloacetate. Enol-oxaloacetate, which is a potent inhibitor of the succinate dehydrogenase activity, is further isomerized into keto-oxaloacetate (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion inner membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR034804 SQR/QFR_C/D
IPR018495 Succ_DH_cyt_bsu_CS
IPR014314 Succ_DH_cytb556
IPR000701 SuccDH_FuR_B_TM-su

The S-nitrosylation sites of Q9CZB0

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 107 ESYLMFVKSL C LGPTLIYSAK  CHHHHHHHHH H HHHHHHHCHH  5.5% 21278135
2 70 KWSLPMALSV C HRGSGIALSG  CHHHHHHHHH H HHHHHHHCHH  1.3% 21278135