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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Mitochondrial outer membrane protein SLC25A46

UniprotKB/SwissProt ID: Q9CQS4 (Q9CQS4)

Gene Name: Slc25a46

Organism: Mus musculus (Mouse)

Function: Transmembrane protein of the mitochondrial outer membrane that controls mitochondrial organization. May regulate the assembly of the MICOS (mitochondrial contact site and cristae organizing system) complex which is essential to the biogenesis and dynamics of mitochondrial cristae, the inwards folds of the inner mitochondrial membrane. Through its interaction with the EMC (endoplasmic reticulum membrane protein complex), could regulate mitochondrial lipid homeostasis and thereby mitochondrial fission

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion outer membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR018108 Mitochondrial_sb/sol_carrier
IPR023395 Mt_carrier_dom_sf
IPR039158 SLC25A46

The S-nitrosylation sites of Q9CQS4

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 127 AHPCIVLRRQ C QVNYHARHYH  CCCCCCCCCC C CCCCCCCCCC  4.65% 21278135