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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Acyl-coenzyme A thioesterase 13

UniprotKB/SwissProt ID: Q9CQR4 (Q9CQR4)

Gene Name: Acot13

Organism: Mus musculus (Mouse)

Function: Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels (PubMed:19405909). Has acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates (PubMed:19405909). Can also hydrolyze 3-hydroxyphenylacetyl-CoA and 3,4-dihydroxyphenylacetyl-CoA (in vitro) (By similarity). May play a role in controlling adaptive thermogenesis (PubMed:24072708)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytosol. Mitochondrion. Nucleus. Cytoplasm, cytoskeleton, spindle

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR039298 ACOT13
IPR029069 HotDog_dom_sf
IPR003736 PAAI_dom
IPR006683 Thioestr_dom

The S-nitrosylation sites of Q9CQR4

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 40 LVSAAPEKLI C EMKVEEQHTN  CCCHHHHHHH H HHHHHCCCCH  6.39% 21278135
2 74 VDSISTMALM C TERGAPGVSV  CCCHHHHHHH H HHHHHCCCCH  3.58% 21278135