Protein Name:
Mitochondrial fission 1 protein
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UniprotKB/SwissProt ID: Q9CQ92 (Q9CQ92)
Gene Name:
Fis1
Organism: Mus musculus (Mouse)
Function: Involved in the fragmentation of the mitochondrial network and its perinuclear clustering (PubMed:23283981). Plays a minor role in the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface and mitochondrial fission (PubMed:23283981). May not be essential for the assembly of functional fission complexes and the subsequent membrane scission event (By similarity). Also mediates peroxisomal fission (By similarity). May act when the products of fission are directed toward mitochondrial homeostasis, mitophagy, or apoptosis (By similarity). Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Mitochondrion outer membrane. Peroxisome membrane
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q9CQ92
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
41 |
SKSTQFEYAW C LVRSKYNEDI |
CHHHHHHCCC H HHHHHHHHHH |
1.59% |
20925432
21278135
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