Protein Name:
S-methyl-5'-thioadenosine phosphorylase
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UniprotKB/SwissProt ID: Q9CQ65 (Q9CQ65)
Gene Name:
Mtap
Organism: Mus musculus (Mouse)
Function: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Nucleus
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q9CQ65
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
130 |
RPQTFYDGSH C SARGVCHIPM |
CCCCCCCCEE E EEEECCCCCC |
3.49% |
20925432
21278135
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| 2 |
136 |
DGSHCSARGV C HIPMAEPFCP |
CCCCCCCCEE E EEEECCCCCC |
2.41% |
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| 3 |
163 |
IETAKKLGLR C HSKGTIVTIE |
CCCCCCCCEE E EEEECCCCCC |
5.23% |
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| 4 |
55 |
LILGKIKNVD C VLLARHGRQH |
CCCCCCCCEE E EEEECCCCCC |
1.7% |
21278135
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