Protein Name:
Cytosol aminopeptidase
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UniprotKB/SwissProt ID: Q9CPY7 (Q9CPY7)
Gene Name:
Lap3
Organism: Mus musculus (Mouse)
Function: Cytosolic metallopeptidase that catalyzes the removal of unsubstituted N-terminal hydrophobic amino acids from various peptides. The presence of Zn(2+) ions is essential for the peptidase activity, and the association with other cofactors can modulate the substrate spectificity of the enzyme. For instance, in the presence of Mn(2+), it displays a specific Cys-Gly hydrolyzing activity of Cys-Gly-S-conjugates. Involved in the metabolism of glutathione and in the degradation of glutathione S-conjugates, which may play a role in the control of the cell redox status
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q9CPY7
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
313 |
RADMGGAATI C SAIVSAAKLN |
CCCCCCHHHH H HHHHHHCCCC |
1.63% |
21278135
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| 2 |
335 |
PINIIGLAPL C ENMPSGKANK |
CCCCCCHHHH H HHHHHHCCCC |
3.28% |
21278135
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| 3 |
376 |
EGRLILADAL C YAHTFNPKVI |
CCCCCCHHHH H HHHHHHCCCC |
2.78% |
21278135
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| 4 |
445 |
FEHYTRQVID C QLADVNNLGK |
CCCCCCHHHH H HHHHHHCCCC |
2.16% |
22178444
21278135
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| 5 |
462 |
NLGKYRSAGA C TAAAFLREFV |
CCCCCCHHHH H HHHHHHCCCC |
2.32% |
21278135
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