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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: RING finger protein unkempt homolog

UniprotKB/SwissProt ID: Q9C0B0 (Q9C0B0)

Gene Name: UNK

Organism: Homo sapiens (Human)

Function: Sequence-specific RNA-binding protein which plays an important role in the establishment and maintenance of the early morphology of cortical neurons during embryonic development. Acts as a translation repressor and controls a translationally regulated cell morphology program to ensure proper structuring of the nervous system. Translational control depends on recognition of its binding element within target mRNAs which consists of a mandatory UAG trimer upstream of a U/A-rich motif. Associated with polysomes (PubMed:25737280)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR045234 Unkempt-like
IPR040594 Unkempt_Znf
IPR000571 Znf_CCCH
IPR036855 Znf_CCCH_sf

The S-nitrosylation sites of Q9C0B0

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 696 GERASAAGAE C ELAREQRDAL   
2 90 GTFNYSPDVY C TKYDEATGLC