Protein Name:
Tripartite motif-containing protein 2
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UniprotKB/SwissProt ID: Q9C040 (Q9C040)
Gene Name:
TRIM2
Organism: Homo sapiens (Human)
Function: UBE2D1-dependent E3 ubiquitin-protein ligase that mediates the ubiquitination of NEFL and of phosphorylated BCL2L11. Plays a neuroprotective function. May play a role in neuronal rapid ischemic tolerance. Plays a role in antiviral immunity and limits New World arenavirus infection independently of its ubiquitin ligase activity (PubMed:24068738)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q9C040
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
254 |
LLQGQESIKS C SNFTAQALNH |
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37478858
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| 2 |
597 |
GHIIVVDNKA C CVFIFQPNGK |
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37478858
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| 3 |
598 |
HIIVVDNKAC C VFIFQPNGKI |
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37478858
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