Protein Name:
Apoptosis inhibitor 5
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UniprotKB/SwissProt ID: Q9BZZ5 (Q9BZZ5)
Gene Name:
API5
Organism: Homo sapiens (Human)
Function: Antiapoptotic factor that may have a role in protein assembly. Negatively regulates ACIN1. By binding to ACIN1, it suppresses ACIN1 cleavage from CASP3 and ACIN1-mediated DNA fragmentation. Also known to efficiently suppress E2F1-induced apoptosis. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus. Cytoplasm. Cytoplasm
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q9BZZ5
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
234 |
EQTFNPSDPD C VDRLLQCTRQ |
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| 2 |
71 |
DSAINAQLDL C EDEDVSIRRQ |
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