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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Dedicator of cytokinesis protein 9

UniprotKB/SwissProt ID: Q9BZ29 (Q9BZ29)

Gene Name: DOCK9

Organism: Homo sapiens (Human)

Function: Guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP. Overexpression induces filopodia formation

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Endomembrane system

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR016024 ARM-type_fold
IPR037809 C2_Dock-D
IPR027007 C2_DOCK-type_domain
IPR035892 C2_domain_sf
IPR026791 DOCK
IPR021816 DOCK_C/D_N
IPR043161 DOCK_C_lobe_A
IPR043162 DOCK_C_lobe_C
IPR027357 DOCKER_dom
IPR046769 DOCKER_Lobe_A
IPR046770 DOCKER_Lobe_B
IPR046773 DOCKER_Lobe_C
IPR011993 PH-like_dom_sf
IPR001849 PH_domain

The S-nitrosylation sites of Q9BZ29

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 628 ITFEVEEFVP C IPKHTQPYTI