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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Protein LSM14 homolog B

UniprotKB/SwissProt ID: Q9BX40 (Q9BX40)

Gene Name: LSM14B

Organism: Homo sapiens (Human)

Function: mRNA-binding protein essential for female fertility, oocyte meiotic maturation and the assembly of MARDO (mitochondria-associated ribonucleoprotein domain), a membraneless compartment that stores maternal mRNAs in oocytes. Ensures the proper accumulation and clearance of mRNAs essential for oocyte meiotic maturation and the normal progression from Meiosis I to Meiosis II in oocytes. Promotes the translation of some oogenesis-related mRNAs. Regulates the expression and/or localization of some key P-body proteins in oocytes. Essential for the assembly of the primordial follicle in the ovary

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, Cytoplasmic ribonucleoprotein granule

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR025762 DFDF
IPR019050 FDF_dom
IPR025761 FFD_box
IPR025609 Lsm14-like_N
IPR010920 LSM_dom_sf
IPR047575 Sm
IPR025768 TFG_box

The S-nitrosylation sites of Q9BX40

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 310 PAEEDLLGPN C YYDKSKSFFD