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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Dual specificity protein phosphatase 23

UniprotKB/SwissProt ID: Q9BVJ7 (Q9BVJ7)

Gene Name: DUSP23

Organism: Homo sapiens (Human)

Function: Protein phosphatase that mediates dephosphorylation of proteins phosphorylated on Tyr and Ser/Thr residues. In vitro, it can dephosphorylate p44-ERK1 (MAPK3) but not p54 SAPK-beta (MAPK10) in vitro. Able to enhance activation of JNK and p38 (MAPK14)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytosol. Nucleus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR029021 Prot-tyrosine_phosphatase-like
IPR050561 PTP
IPR057023 PTP-SAK
IPR016130 Tyr_Pase_AS
IPR003595 Tyr_Pase_cat
IPR000387 Tyr_Pase_dom
IPR020422 TYR_PHOSPHATASE_DUAL_dom

The S-nitrosylation sites of Q9BVJ7

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 67 TLHRLRIPDF C PPAPDQIDRF