Protein Name:
Tubulin beta-2B chain
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UniprotKB/SwissProt ID: Q9BVA1 (Q9BVA1)
Gene Name:
TUBB2B
Organism: Homo sapiens (Human)
Function: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers (PubMed:23001566, PubMed:26732629, PubMed:28013290). Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin. Plays a critical role in proper axon guidance in both central and peripheral axon tracts (PubMed:23001566). Implicated in neuronal migration (PubMed:19465910)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm, cytoskeleton
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q9BVA1
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
12 |
REIVHIQAGQ C GNQIGAKFWE |
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| 2 |
127 |
LDVVRKESES C DCLQGFQLTH |
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37478858
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| 3 |
129 |
VVRKESESCD C LQGFQLTHSL |
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37478858
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| 4 |
239 |
VSATMSGVTT C LRFPGQLNAD |
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37478858
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| 5 |
303 |
MFDSKNMMAA C DPRHGRYLTV |
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37478858
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| 6 |
354 |
WIPNNVKTAV C DIPPRGLKMS |
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