Protein Name:
tRNA (guanine(6)-N(2))-methyltransferase THUMP3
|
UniprotKB/SwissProt ID: Q9BV44 (Q9BV44)
Gene Name:
THUMPD3
Organism: Homo sapiens (Human)
Function: Catalytic subunit of the THUMPD3-TRM112 methyltransferase complex, that specifically mediates the S-adenosyl-L-methionine-dependent N(2)-methylation of guanosine nucleotide at position 6 (m2G6) in tRNAs (PubMed:34669960, PubMed:37283053). This is one of the major tRNA (guanine-N(2))-methyltransferases (PubMed:37283053). Also catalyzes the S-adenosyl-L-methionine-dependent N(2)-methylation of guanosine nucleotide at position 7 of tRNA(Trp) (PubMed:34669960)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm
|
|
|
Graphical Visualization of S-nitrosylation Sites:
|
|
The S-nitrosylation sites of Q9BV44
|
| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
208 |
STLIGDDLAS C KDETDESSKE |
|
|
|
| 2 |
239 |
VTCNRAGEKH C FTSNEAARDF |
|
|
|
| 3 |
426 |
KKRNWNLYPA C LREMSRVCTP |
|
|
|
|
