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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Heterogeneous nuclear ribonucleoprotein U-like protein 1

UniprotKB/SwissProt ID: Q9BUJ2 (Q9BUJ2)

Gene Name: HNRNPUL1

Organism: Homo sapiens (Human)

Function: Acts as a basic transcriptional regulator. Represses basic transcription driven by several virus and cellular promoters. When associated with BRD7, activates transcription of glucocorticoid-responsive promoter in the absence of ligand-stimulation. Also plays a role in mRNA processing and transport. Binds avidly to poly(G) and poly(C) RNA homopolymers in vitro

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR001870 B30.2/SPRY
IPR043136 B30.2/SPRY_sf
IPR013320 ConA-like_dom_sf
IPR027417 P-loop_NTPase
IPR003034 SAP_dom
IPR036361 SAP_dom_sf
IPR003877 SPRY_dom
IPR035778 SPRY_hnRNP_U

The S-nitrosylation sites of Q9BUJ2

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 291 VVRIGWSLDS C STQLGEEPFS  CCHHHHHHHH H HHHHHHCCCC  5.21%
2 337 DVIGCFADFE C GNDVELSFTK  CCHHHHHHHH H HHHHHHCCCC  6.61%
3 377 ALYPHVLVKN C AVEFNFGQRA  CCHHHHHHHH H HHHHHHCCCC  3.58% 22178444
18335467
4 391 FNFGQRAEPY C SVLPGFTFIQ  CCHHHHHHHH H HHHHHHCCCC  3.12%
5 421 GTVGPKSKAE C EILMMVGLPA  CCHHHHHHHH H HHHHHHCCCC  4.75%
6 487 WDVLIQQATQ C LNRLIQIAAR  CCHHHHHHHH H HHHHHHCCCC  2.94% 22178444
18335467
7 532 EGFQRKAIVI C PTDEDLKDRT  CCHHHHHHHH H HHHHHHCCCC  1.74%