Protein Name:
DCN1-like protein 5
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UniprotKB/SwissProt ID: Q9BTE7 (Q9BTE7)
Gene Name:
DCUN1D5
Organism: Homo sapiens (Human)
Function: Contributes to the neddylation of all cullins by transferring NEDD8 from N-terminally acetylated NEDD8-conjugating E2s enzyme to different cullin C-terminal domain-RBX complexes which is necessary for the activation of cullin-RING E3 ubiquitin ligases (CRLs) (PubMed:19617556, PubMed:23201271, PubMed:26906416). May play a role in DNA damage response and may participate in cell proliferation and anchorage-independent cell growth (PubMed:23098533, PubMed:24192928)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus. Cytoplasm, cytoskeleton, spindle
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q9BTE7
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
115 |
EWLKGMTSLQ C DCTEKLQNKF |
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| 2 |
117 |
LKGMTSLQCD C TEKLQNKFDF |
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| 3 |
31 |
GLKKCKISSY C RSQPPARLIS |
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