Protein Name:
Fermitin family homolog 1
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UniprotKB/SwissProt ID: Q9BQL6 (Q9BQL6)
Gene Name:
FERMT1
Organism: Homo sapiens (Human)
Function: Involved in cell adhesion. Contributes to integrin activation. When coexpressed with talin, potentiates activation of ITGA2B. Required for normal keratinocyte proliferation. Required for normal polarization of basal keratinocytes in skin, and for normal cell shape. Required for normal adhesion of keratinocytes to fibronectin and laminin, and for normal keratinocyte migration to wound sites. May mediate TGF-beta 1 signaling in tumor progression
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm, cytoskeleton. Cell junction, focal adhesion. Cell projection, ruffle membrane
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q9BQL6
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
423 |
EPLEKLNLRG C EVVPDVNVAG |
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| 2 |
517 |
SLENMDMNPE C FVSPRCAKRH |
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