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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Myb-binding protein 1A

UniprotKB/SwissProt ID: Q9BQG0 (Q9BQG0)

Gene Name: MYBBP1A

Organism: Homo sapiens (Human)

Function: May activate or repress transcription via interactions with sequence specific DNA-binding proteins (By similarity). Repression may be mediated at least in part by histone deacetylase activity (HDAC activity) (By similarity). Acts as a corepressor and in concert with CRY1, represses the transcription of the core circadian clock component PER2 (By similarity). Preferentially binds to dimethylated histone H3 'Lys-9' (H3K9me2) on the PER2 promoter (By similarity). Has a role in rRNA biogenesis together with PWP1 (PubMed:29065309)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Nucleus. Nucleus, nucleolus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR007015 DNA_pol_V/MYBBP1A

The S-nitrosylation sites of Q9BQG0

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 1031 TGPVRPRHQA C LLLQKTLSMR  CCCCCCCCCC C CCCCCCCCCC  1.9% 19483679
2 1046 KTLSMREVRS C FEDPEWKQLM  CCCCCCCCCC C CCCCCCCCCC  2.8%
3 338 DVIRHYGEHV C TAKLPKQFKF  CCCCCCCCCC C CCCCCCCCCC  3.1%
4 363 DDYVGTFLEG C QDDPERQLAV  CCCCCCCCCC C CCCCCCCCCC  2.68%
5 614 IHLLKSPAES C DLLGDIQTCI  CCCCCCCCCC C CCCCCCCCCC  3%
6 678 QVARSVFGHI C SHLTPRALQL  CCCCCCCCCC C CCCCCCCCCC  1.41%
7 884 KTARIFTHHL C RARRYCHDLG  CCCCCCCCCC C CCCCCCCCCC  2.51%
8 890 THHLCRARRY C HDLGERAGAL  CCCCCCCCCC C CCCCCCCCCC  1.59%
9 942 RVLKGNTAEG C VHETQEKQKA  CCCCCCCCCC C CCCCCCCCCC  1.81%
10 968 HMPTGPQAAS C LDLNLVTRVY  CCCCCCCCCC C CCCCCCCCCC  2.69%