Protein Name:
TOX high mobility group box family member 4
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UniprotKB/SwissProt ID: Q99PM1 (Q99PM1)
Gene Name:
Tox4
Organism: Rattus norvegicus (Rat)
Function: Transcription factor that modulates cell fate reprogramming from the somatic state to the pluripotent and neuronal fate. In liver, controls the expression of hormone-regulated gluconeogenic genes such as G6PC1 and PCK1. This regulation is independent of the insulin receptor activation. Also acts as a regulatory component of protein phosphatase 1 (PP1) complexes. Component of the PNUTS-PP1 protein phosphatase complex, a PP1 complex that regulates RNA polymerase II transcription pause-release (By similarity). PNUTS-PP1 also plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus. Chromosome
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q99PM1
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
575 |
SPQPRCVRSG C ENPPVISKDW |
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