UniprotKB/SwissProt ID: Q99P58 (Q99P58)
Gene Name:
Rab27b
Organism: Mus musculus (Mouse)
Function: Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate homeostasis of late endocytic pathway, including endosomal positioning, maturation and secretion (By similarity). Plays a role in NTRK2/TRKB axonal anterograde transport by facilitating the association of NTRK2/TRKB with KLC1 (By similarity). May be involved in targeting uroplakins to urothelial apical membranes (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Membrane. Late endosome
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