Protein Name:
Leupaxin
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UniprotKB/SwissProt ID: Q99N69 (Q99N69)
Gene Name:
Lpxn
Organism: Mus musculus (Mouse)
Function: Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin-induced tyrosine phosphorylation of paxillin (PXN). May play a critical role as an adapter protein in the formation of the adhesion zone in osteoclasts. Negatively regulates B-cell antigen receptor (BCR) signaling
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Cell junction, focal adhesion. Nucleus. Cytoplasm, perinuclear region. Cell projection, podosome. Cell membrane
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q99N69
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
211 |
KDYHRLFSPR C AYCAAPITDK |
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| 2 |
329 |
LHYHHRRGTL C HDCGQPITGR |
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