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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: RNA-splicing ligase RtcB homolog

UniprotKB/SwissProt ID: Q99LF4 (Q99LF4)

Gene Name: Rtcb

Organism: Mus musculus (Mouse)

Function: Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs (By similarity). Essential during post-implantation development of embryos

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus. Cytoplasm

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR001233 RtcB
IPR036025 RtcB-like_sf
IPR027513 RtcB_euk

The S-nitrosylation sites of Q99LF4

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 255 KMGIDHKGQV C VMIHSGSRGL  CCCCCHHHHH H HHHHHHCCCC  1.01% 21278135
2 485 YKNVTDVVNT C HDAGISKKAI  CCCCCHHHHH H HHHHHHCCCC  2%