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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Dehydrogenase/reductase SDR family member 1

UniprotKB/SwissProt ID: Q99L04 (Q99L04)

Gene Name: Dhrs1

Organism: Mus musculus (Mouse)

Function: NADPH-dependent oxidoreductase which catalyzes the reduction of some steroids (estrone, androstene-3,17-dione and cortisone) as well as prostaglandin E1, isatin and xenobiotics in vitro. May have a role in steroid and/or xenobiotic metabolism

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Endoplasmic reticulum

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR036291 NAD(P)-bd_dom_sf
IPR002347 SDR_fam

The S-nitrosylation sites of Q99L04

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 10 -MVAPMKGQV C VVTGASRGIG  CCCCCCCCEE E EECCCCCCCH  1.24% 21278135
2 130 NNVGLRGHYL C SVYGARLMVP  CCCCCCCCEE E EECCCCCCCH  1.72%
3 177 KAACDRLAAD C AHELRRHGVS  CCCCCCCCEE E EECCCCCCCH  3.41% 21278135
4 235 SAESPEMSGK C VVALATDPNI  CCCCCCCCEE E EECCCCCCCH  3.21%
5 58 AQEAQSLGGR C VPVVCDSSQE  CCCCCCCCEE E EECCCCCCCH  4.6%