Protein Name:
Trifunctional enzyme subunit beta, mitochondrial
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UniprotKB/SwissProt ID: Q99JY0 (Q99JY0)
Gene Name:
Hadhb
Organism: Mus musculus (Mouse)
Function: Mitochondrial trifunctional enzyme catalyzes the last three of the four reactions of the mitochondrial beta-oxidation pathway. The mitochondrial beta-oxidation pathway is the major energy-producing process in tissues and is performed through four consecutive reactions breaking down fatty acids into acetyl-CoA. Among the enzymes involved in this pathway, the trifunctional enzyme exhibits specificity for long-chain fatty acids. Mitochondrial trifunctional enzyme is a heterotetrameric complex composed of two proteins, the trifunctional enzyme subunit alpha/HADHA carries the 2,3-enoyl-CoA hydratase and the 3-hydroxyacyl-CoA dehydrogenase activities, while the trifunctional enzyme subunit beta/HADHB described here bears the 3-ketoacyl-CoA thiolase activity
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Mitochondrion. Mitochondrion inner membrane. Mitochondrion outer membrane. Endoplasmic reticulum
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q99JY0
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
436 |
SLGHPFGATG C RLVMAAANRL |
CCEEECHHCC C CCCCCHHHHH |
2.36% |
21278135
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| 2 |
459 |
DGGQYALVAA C AAGGQGHAMI |
CCEEECHHCC C CCCCCHHHHH |
1.6% |
21278135
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