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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: LIM and senescent cell antigen-like-containing domain protein 1

UniprotKB/SwissProt ID: Q99JW4 (Q99JW4)

Gene Name: Lims1

Organism: Mus musculus (Mouse)

Function: Within the IPP (ILK-PINCH-PARVIN) complex, binds to F-actin, promoting F-actin bundling, a process required to generate force for actin cytoskeleton reorganization and subsequent dynamic cell adhesion events such as cell spreading and migration

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cell junction, focal adhesion. Cell membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR047944 LIMS1/2-like_LIM1
IPR017351 PINCH-1-4-like
IPR047946 PINCH-1/2-like
IPR001781 Znf_LIM

The S-nitrosylation sites of Q99JW4

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 222 WHVEHFVCAK C EKPFLGHRHY  CCHHHHHHHH H HCCCCCCCHH  4.29% 21278135
2 303 EFDMKPVCKK C YEKFPLELKK  CCHHHHHHHH H HCCCCCCCHH  3.03%
3 94 KAMNNSWHPE C FRCDLCQEVL  CCHHHHHHHH H HCCCCCCCHH  2.84% 21278135