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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: 26S proteasome non-ATPase regulatory subunit 6

UniprotKB/SwissProt ID: Q99JI4 (Q99JI4)

Gene Name: Psmd6

Organism: Mus musculus (Mouse)

Function: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR000717 PCI_dom
IPR019585 Rpn7/CSN1
IPR045135 Rpn7_N
IPR049549 RPN7_PSMD6_C
IPR011990 TPR-like_helical_dom_sf
IPR036390 WH_DNA-bd_sf

The S-nitrosylation sites of Q99JI4

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 112 DAMMAKAEYL C QIGDKEGALT