Protein Name:
Protein kinase C and casein kinase II substrate protein 3
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UniprotKB/SwissProt ID: Q99JB8 (Q99JB8)
Gene Name:
Pacsin3
Organism: Mus musculus (Mouse)
Function: Plays a role in endocytosis and regulates internalization of plasma membrane proteins. Overexpression impairs internalization of SLC2A1/GLUT1 and TRPV4 and increases the levels of SLC2A1/GLUT1 and TRPV4 at the cell membrane. Inhibits the TRPV4 calcium channel activity
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Cell membrane
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q99JB8
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
231 |
MEDMEQAFES C QAAERQRLLF |
CCCHHHCCCC C CCCCHHCCCC |
2.22% |
21278135
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| 2 |
402 |
KMSEEDEQGW C QGQLQSGRIG |
CCCHHHCCCC C CCCCHHCCCC |
4.1% |
21278135
|
| 3 |
421 |
IGLYPANYVE C VGA------- |
CCCHHHCCCC C CCCCHHCCCC |
2.14% |
21278135
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