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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Ataxin-2

UniprotKB/SwissProt ID: Q99700 (Q99700)

Gene Name: ATXN2

Organism: Homo sapiens (Human)

Function: Involved in EGFR trafficking, acting as negative regulator of endocytic EGFR internalization at the plasma membrane

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR045117 ATXN2-like
IPR010920 LSM_dom_sf
IPR009604 LsmAD_domain
IPR009818 PAM2_motif
IPR047575 Sm
IPR025852 SM_dom_ATX

The S-nitrosylation sites of Q99700

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 280 HILTSVVGSK C EVQVKNGGIY  CCCCCCCCCC C CCCCCCHHHH  7.11%
2 301 EGVFKTYSPK C DLVLDAAHEK  CCCCCCCCCC C CCCCCCHHHH  5.77% 19483679
24105792
3 852 DSFIENSSSN C TSGSSKPNSP  CCCCCCCCCC C CCCCCCHHHH  3.28%
4 892 SQGVQTSSPA C KQEKDDKEEK  CCCCCCCCCC C CCCCCCHHHH  5.47%