Protein Name:
Kinesin-like protein KIF2C
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UniprotKB/SwissProt ID: Q99661 (Q99661)
Gene Name:
KIF2C
Organism: Homo sapiens (Human)
Function: In complex with KIF18B, constitutes the major microtubule plus-end depolymerizing activity in mitotic cells (PubMed:21820309). Regulates the turnover of microtubules at the kinetochore and functions in chromosome segregation during mitosis (PubMed:19060894). Plays a role in chromosome congression and is required for the lateral to end-on conversion of the chromosome-microtubule attachment (PubMed:23891108)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm, cytoskeleton. Nucleus. Chromosome, centromere. Chromosome, centromere, kinetochore
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q99661
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
344 |
QTIFEGGKAT C FAYGQTGSGK |
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| 2 |
389 |
RDVFLLKNQP C YRKLGLEVYV |
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| 3 |
40 |
NVRTVNLEKS C VSVEWAEGGA |
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| 4 |
455 |
VIKMIDMGSA C RTSGQTFANS |
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