Protein Name:
DnaJ homolog subfamily C member 7
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UniprotKB/SwissProt ID: Q99615 (Q99615)
Gene Name:
DNAJC7
Organism: Homo sapiens (Human)
Function: Acts as a co-chaperone regulating the molecular chaperones HSP70 and HSP90 in folding of steroid receptors, such as the glucocorticoid receptor and the progesterone receptor. Proposed to act as a recycling chaperone by facilitating the return of chaperone substrates to early stages of chaperoning if further folding is required. In vitro, induces ATP-independent dissociation of HSP90 but not of HSP70 from the chaperone-substrate complexes. Recruits NR1I3 to the cytoplasm (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Nucleus. Cytoplasm, cytoskeleton
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q99615
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
105 |
FVRGHLREGK C HLSLGNAMAA |
CCCHHCCCEE E EECCHHHCCH |
6% |
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| 2 |
116 |
HLSLGNAMAA C RSFQRALELD |
CCCHHCCCEE E EECCHHHCCH |
2.45% |
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| 3 |
164 |
EKRDFRKVVF C MDRALEFAPA |
CCCHHCCCEE E EECCHHHCCH |
1.55% |
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| 4 |
175 |
MDRALEFAPA C HRFKILKAEC |
CCCHHCCCEE E EECCHHHCCH |
2% |
19483679
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| 5 |
185 |
CHRFKILKAE C LAMLGRYPEA |
CCCHHCCCEE E EECCHHHCCH |
3.33% |
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| 6 |
219 |
NADALYVRGL C LYYEDCIEKA |
CCCHHCCCEE E EECCHHHCCH |
2.27% |
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| 7 |
225 |
VRGLCLYYED C IEKAVQFFVQ |
CCCHHCCCEE E EECCHHHCCH |
2.64% |
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| 8 |
247 |
LRMAPDHEKA C IACRNAKALK |
CCCHHCCCEE E EECCHHHCCH |
2.76% |
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| 9 |
317 |
LRKLDDAIED C TNAVKLDDTY |
CCCHHCCCEE E EECCHHHCCH |
1.73% |
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| 10 |
337 |
YIKAYLRRAQ C YMDTEQYEEA |
CCCHHCCCEE E EECCHHHCCH |
2.72% |
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