Protein Name:
Phosphoinositide 3-kinase regulatory subunit 4
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UniprotKB/SwissProt ID: Q99570 (Q99570)
Gene Name:
PIK3R4
Organism: Homo sapiens (Human)
Function: Regulatory subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and cytokinesis, probably in the context of PI3KC3-C2 (PubMed:20643123)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Late endosome. Cytoplasmic vesicle, autophagosome. Membrane
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q99570
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
1011 |
VSDEHSLFAT C SNDGTVKIWN |
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| 2 |
693 |
ARQISTADVY C KLMPYLDPYI |
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| 3 |
899 |
PPRSESSAGI C VPLSTSSQVP |
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