\
logo
  Home | Contact us | Browse | Quick Search by UniProtKB ID, Keyword, PDBID

Menu:

Latest news:

Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

Read more...


Protein Name: Calponin-2

UniprotKB/SwissProt ID: Q99439 (Q99439)

Gene Name: CNN2

Organism: Homo sapiens (Human)

Function: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR050606 Calponin-like
IPR001997 Calponin/LIMCH1
IPR000557 Calponin_repeat
IPR001715 CH_dom
IPR036872 CH_dom_sf
IPR003096 SM22_calponin

The S-nitrosylation sites of Q99439

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 164 FDDATMKAGQ C VIGLQMGTNK  CCCCCCCCCC C CCCCHHHHHH  2.05% 22178444
20140087
2 175 VIGLQMGTNK C ASQSGMTAYG  CCCCCCCCCC C CCCCHHHHHH  4.83%
3 215 TISLQMGTNK C ASQVGMTAPG  CCCCCCCCCC C CCCCHHHHHH  4.83% 2212679
4 240 IYDTKLGTDK C DNSSMSLQMG  CCCCCCCCCC C CCCCHHHHHH  7.15%
5 290 ADGAPSGTGD C PDPGEVPEYP  CCCCCCCCCC C CCCCHHHHHH  4.33%
6 61 QKGLKDGTIL C TLMNKLQPGS  CCCCCCCCCC C CCCCHHHHHH  2.13% 22178444
20140087