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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Tubulin-folding cofactor B

UniprotKB/SwissProt ID: Q99426 (Q99426)

Gene Name: TBCB

Organism: Homo sapiens (Human)

Function: Binds to alpha-tubulin folding intermediates after their interaction with cytosolic chaperonin in the pathway leading from newly synthesized tubulin to properly folded heterodimer (PubMed:9265649). Involved in regulation of tubulin heterodimer dissociation. May function as a negative regulator of axonal growth (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Cytoplasm, cytoskeleton

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR036859 CAP-Gly_dom_sf
IPR000938 CAP-Gly_domain
IPR045172 TBCB_Ubl
IPR000626 Ubiquitin-like_dom
IPR029071 Ubiquitin-like_domsf

The S-nitrosylation sites of Q99426

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 165 QASSIPVGSR C EVRAAGQSPR   
2 83 LLGSYPVDDG C RIHVIDHSGA