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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Myosin heavy chain, non-muscle

UniprotKB/SwissProt ID: Q99323 (Q99323)

Gene Name: zip

Organism: Drosophila melanogaster (Fruit fly)

Function: Nonmuscle myosin appears to be responsible for cellularization. Required for morphogenesis and cytokinesis (PubMed:24786584). Necessary for auditory transduction: plays a role in Johnston's organ organization by acting in scolopidial apical attachment (PubMed:27331610). Interaction with the myosin ck may be important for this function (PubMed:27331610). Localizes to and defines the trailing edge of cells during larval epidermal wound healing (PubMed:31704968). This process is dependent on the phosphatidylinositol 4-phosphate 5-kinase sktl/skittles (PubMed:31704968)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cell projection, cilium. Cytoplasm

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR000048 IQ_motif_EF-hand-BS
IPR036961 Kinesin_motor_dom_sf
IPR001609 Myosin_head_motor_dom-like
IPR004009 Myosin_N
IPR008989 Myosin_S1_N
IPR002928 Myosin_tail
IPR027417 P-loop_NTPase