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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Transcription factor 12

UniprotKB/SwissProt ID: Q99081 (Q99081)

Gene Name: TCF12

Organism: Homo sapiens (Human)

Function: Transcriptional regulator. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3') (By similarity). May be involved in the functional network that regulates the development of the GnRH axis (PubMed:32620954)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR011598 bHLH_dom
IPR036638 HLH_DNA-bd_sf
IPR051098 NeuroDiff_E-box_TFs

The S-nitrosylation sites of Q99081

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 129 LYSRDTGLPG C QSSLLRQDLG