Protein Name:
Pleckstrin homology domain-containing family F member 1
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UniprotKB/SwissProt ID: Q96S99 (Q96S99)
Gene Name:
PLEKHF1
Organism: Homo sapiens (Human)
Function: May induce apoptosis through the lysosomal-mitochondrial pathway. Translocates to the lysosome initiating the permeabilization of lysosomal membrane (LMP) and resulting in the release of CTSD and CTSL to the cytoplasm. Triggers the caspase-independent apoptosis by altering mitochondrial membrane permeabilization (MMP) resulting in the release of PDCD8
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus. Cytoplasm, perinuclear region. Lysosome
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q96S99
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
207 |
SPKPVRVCSL C YRELAAQQRQ |
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