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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: ATPase WRNIP1

UniprotKB/SwissProt ID: Q96S55 (Q96S55)

Gene Name: WRNIP1

Organism: Homo sapiens (Human)

Function: Functions as a modulator of initiation or reinitiation events during DNA polymerase delta-mediated DNA synthesis. In the presence of ATP, stimulation of DNA polymerase delta-mediated DNA synthesis is decreased. Also plays a role in the innate immune defense against viruses. Stabilizes the RIGI dsRNA interaction and promotes RIGI 'Lys-63'-linked polyubiquitination. In turn, RIGI transmits the signal through mitochondrial MAVS

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus. Cytoplasm

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR003593 AAA+_ATPase
IPR032423 AAA_assoc_2
IPR051314 AAA_ATPase_RarA/MGS1/WRNIP1
IPR003959 ATPase_AAA_core
IPR008921 DNA_pol3_clamp-load_cplx_C
IPR021886 MgsA_C
IPR027417 P-loop_NTPase
IPR006642 Rad18_UBZ4
IPR040539 Znf-WRNIP1_ubi

The S-nitrosylation sites of Q96S55

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 272 PSLILWGPPG C GKTTLAHIIA