Protein Name:
Erbin
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UniprotKB/SwissProt ID: Q96RT1 (Q96RT1)
Gene Name:
ERBIN
Organism: Homo sapiens (Human)
Function: Acts as an adapter for the receptor ERBB2, in epithelia. By binding the unphosphorylated 'Tyr-1248' of receptor ERBB2, it may contribute to stabilize this unphosphorylated state (PubMed:16203728). Inhibits NOD2-dependent NF-kappa-B signaling and pro-inflammatory cytokine secretion (PubMed:16203728)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell junction, hemidesmosome. Nucleus membrane. Basolateral cell membrane
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q96RT1
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
464 |
RKQRAQVAFE C DEDKDEREAP |
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