Protein Name:
Intermembrane lipid transfer protein VPS13A
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UniprotKB/SwissProt ID: Q96RL7 (Q96RL7)
Gene Name:
VPS13A
Organism: Homo sapiens (Human)
Function: Mediates the transfer of lipids between membranes at organelle contact sites (By similarity). Binds phospholipids (PubMed:34830155). Required for the formation or stabilization of ER-mitochondria contact sites which enable transfer of lipids between the ER and mitochondria (PubMed:30741634). Negatively regulates lipid droplet size and motility (PubMed:30741634). Required for efficient lysosomal protein degradation (PubMed:30709847)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Mitochondrion outer membrane. Endoplasmic reticulum membrane. Endosome membrane. Lysosome membrane. Lipid droplet. Golgi apparatus. Cytoplasmic vesicle, secretory vesicle, neuronal dense core vesicle
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q96RL7
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
1626 |
KGKITTVLQP C DLFYQTTQKG |
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| 2 |
582 |
NPLDETVSQR C IIEAEPLEII |
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