Protein Name:
28S rRNA (cytosine-C(5))-methyltransferase
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UniprotKB/SwissProt ID: Q96P11 (Q96P11)
Gene Name:
NSUN5
Organism: Homo sapiens (Human)
Function: S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C(5) position of cytosine 3782 (m5C3782) in 28S rRNA (PubMed:23913415, PubMed:31428936, PubMed:31722427). m5C3782 promotes protein translation without affecting ribosome biogenesis and fidelity (PubMed:31428936, PubMed:31722427). Required for corpus callosum and cerebral cortex development (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus, nucleolus
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q96P11
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
146 |
RFVRVNTLKT C SDDVVDYFKR |
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| 2 |
359 |
PSLQRLVYST C SLCQEENEDV |
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