Protein Name:
Chloride intracellular channel protein 6
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UniprotKB/SwissProt ID: Q96NY7 (Q96NY7)
Gene Name:
CLIC6
Organism: Homo sapiens (Human)
Function: In the soluble state, catalyzes glutaredoxin-like thiol disulfide exchange reactions with reduced glutathione as electron donor (By similarity). Can insert into membranes and form voltage-dependent chloride-selective channels. The channel opens upon membrane depolarization at positive voltages and closes at negative membrane voltages (PubMed:37838179). May play a critical role in water-secreting cells, possibly through the regulation of chloride ion transport (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Cell membrane
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q96NY7
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
487 |
AGYDGESIGN C PFSQRLFMIL |
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