Protein Name:
Cytosolic non-specific dipeptidase
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UniprotKB/SwissProt ID: Q96KP4 (Q96KP4)
Gene Name:
CNDP2
Organism: Homo sapiens (Human)
Function: Catalyzes the peptide bond hydrolysis in dipeptides, displaying a non-redundant activity toward threonyl dipeptides (By similarity). Mediates threonyl dipeptide catabolism in a tissue-specific way (By similarity). Has high dipeptidase activity toward cysteinylglycine, an intermediate metabolite in glutathione metabolism (PubMed:12473676, PubMed:19346245). Metabolizes N-lactoyl-amino acids, both through hydrolysis to form lactic acid and amino acids, as well as through their formation by reverse proteolysis (PubMed:25964343). Plays a role in the regulation of cell cycle arrest and apoptosis (PubMed:17121880, PubMed:24395568)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q96KP4
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
161 |
GQEIPVNVRF C LEGMEESGSE |
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| 2 |
192 |
DTFFKDVDYV C ISDNYWLGKK |
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| 3 |
214 |
PCITYGLRGI C YFFIEVECSN |
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