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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: N-terminal kinase-like protein

UniprotKB/SwissProt ID: Q96KG9 (Q96KG9)

Gene Name: SCYL1

Organism: Homo sapiens (Human)

Function: Regulates COPI-mediated retrograde protein traffic at the interface between the Golgi apparatus and the endoplasmic reticulum (PubMed:18556652). Involved in the maintenance of the Golgi apparatus morphology (PubMed:26581903) Acts as a transcriptional activator. It binds to three different types of GC-rich DNA binding sites (box-A, -B and -C) in the beta-polymerase promoter region. It also binds to the TERT promoter region

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Endoplasmic reticulum-Golgi intermediate compartment. Golgi apparatus, cis-Golgi network. Cytoplasm. Cytoplasm. Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR051177 CIK-Related_Protein
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom

The S-nitrosylation sites of Q96KG9

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 241 KIPKTLVPHY C ELVGANPKVR    37478858
2 261 RPNPARFLQN C RAPGGFMSNR   
3 309 KSLDAFPEDF C RHKVLPQLLT   
4 512 DCAQKILPVL C GLTVDPEKSV   
5 88 AYIDGLETEK C LHVVTEAVTP