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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Lymphokine-activated killer T-cell-originated protein kinase

UniprotKB/SwissProt ID: Q96KB5 (Q96KB5)

Gene Name: PBK

Organism: Homo sapiens (Human)

Function: Phosphorylates MAP kinase p38. Seems to be active only in mitosis. May also play a role in the activation of lymphoid cells. When phosphorylated, forms a complex with TP53, leading to TP53 destabilization and attenuation of G2/M checkpoint during doxorubicin-induced DNA damage

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR011009 Kinase-like_dom_sf
IPR041989 PKc_TOPK
IPR000719 Prot_kinase_dom
IPR008271 Ser/Thr_kinase_AS

The S-nitrosylation sites of Q96KB5

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 112 AFTEANDGSL C LAMEYGGEKS   
2 205 ENMTVTDPEA C YIGTEPWKPK   
3 22 KLSEKKKSVL C STPTINIPAS   
4 70 PWAVKKINPI C NDHYRSVYQK