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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Ubiquitin carboxyl-terminal hydrolase 47

UniprotKB/SwissProt ID: Q96K76 (Q96K76)

Gene Name: USP47

Organism: Homo sapiens (Human)

Function: Ubiquitin-specific protease that specifically deubiquitinates monoubiquitinated DNA polymerase beta (POLB), stabilizing POLB thereby playing a role in base-excision repair (BER). Acts as a regulator of cell growth and genome integrity. May also indirectly regulate CDC25A expression at a transcriptional level

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR038765 Papain-like_cys_pep_sf
IPR050164 Peptidase_C19
IPR001394 Peptidase_C19_UCH
IPR029071 Ubiquitin-like_domsf
IPR045578 USP47_C
IPR018200 USP_CS
IPR028889 USP_dom

The S-nitrosylation sites of Q96K76

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 1138 YQLLVNEQEP C KFLLDAVFAK   
2 1309 STLNVWPLYI C DDGAVIFYRD   
3 311 YQGKLKDYVR C LECGYEGWRI   
4 45 ENAAEEPRVL C IIQDTTNSKT   
5 856 GGDSGNVDDD C ERVKGPVGSL