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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: PDZ and LIM domain protein 2

UniprotKB/SwissProt ID: Q96JY6 (Q96JY6)

Gene Name: PDLIM2

Organism: Homo sapiens (Human)

Function: Probable adapter protein located at the actin cytoskeleton that promotes cell attachment. Necessary for the migratory capacity of epithelial cells. Overexpression enhances cell adhesion to collagen and fibronectin and suppresses anchorage independent growth. May contribute to tumor cell migratory capacity

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Nucleus. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton. Nucleus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR031847 PDLI1-4/Zasp-like_mid
IPR001478 PDZ
IPR050604 PDZ-LIM_domain
IPR036034 PDZ_sf
IPR001781 Znf_LIM

The S-nitrosylation sites of Q96JY6

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 289 TPPKLHTCEK C STSIANQAVR